[Info.aoa-nano] SmallTalks [about Nanoscience] "Probing liposome binding and deformation using multi-parametric surface plasmon resonance"

[Nano]

On Monday September 18th at 15.00h we welcome you all to our SmallTalk seminar series. You are welcome to join us in lecture hall Kollektorn, MC2 with fika or on zoom.
Our speaker is Karin Norling, Postdoc, Chemical Biology, Life Sciences. The seminar is titled "Probing liposome binding and deformation using multi-parametric surface plasmon resonance".
Abstract:
Liposomes are popular drug delivery carriers and often used to modulate cellular uptake. The initial binding of drug- or vaccine-carrying liposomes to the cell surface is a key step in the uptake process, although not trivial to characterize. Multi-parametric/dual-wavelength surface plasmon resonance (MP-SPR), is a label-free surface-based technique that provides quantification of bound mass as well as structural information in real-time. Here, we present an MP-SPR-based method to simultaneously study multivalent binding and binding-induced deformation of liposomes to a cell membrane mimic, and compare the interaction behavior of two different liposome types.The seminar is divided into two parts, where the first part consists of a pure overview of the field and is held on a generally accessible level (10 min). The second part will be more technical (15-20 minutes).
Looking forward to seeing you live or on Zoom:  https://chalmers.zoom.us/j/63018620593#success
Best regards,
Alexandra, Philippe, Christoph, and Janine

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