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<p class="MsoNormal"><b><span lang="EN-US" style="color:black">On Monday </span></b><b><span lang="EN-US">September 18th
</span></b><span lang="EN-US" style="color:black">at 15.00h</span><span lang="EN-US">
<span style="color:black">we welcome you all to our SmallTalk seminar series. You are welcome to join us in lecture hall <b>Kollektorn, MC2 with fika</b> or on zoom.<o:p></o:p></span></span></p>
<h1><span lang="EN-US" style="font-size:11.0pt;color:black;font-weight:normal">Our speaker is Karin Norling, Postdoc, Chemical Biology, Life Sciences. The seminar is titled “Probing liposome binding and deformation using multi-parametric surface plasmon resonance”.</span><span lang="EN-US" style="font-size:11.0pt;font-weight:normal"><o:p></o:p></span></h1>
<p class="MsoNormal"><b><span lang="EN-US" style="color:black">Abstract:<o:p></o:p></span></b></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black">Liposomes are popular drug delivery carriers and often used to modulate cellular uptake. The initial binding of drug- or vaccine-carrying liposomes to the cell surface is a key step in the uptake process,
although not trivial to characterize. Multi-parametric/dual-wavelength surface plasmon resonance (MP-SPR), is a label-free surface-based technique that provides quantification of bound mass as well as structural information in real-time. Here, we present an
MP-SPR-based method to simultaneously study multivalent binding and binding-induced deformation of liposomes to a cell membrane mimic, and compare the interaction behavior of two different liposome types.The seminar is divided into two parts, where the first
part consists of a pure overview of the field and is held on a generally accessible level (10<span class="apple-converted-space"> </span>min). The second part will be more technical (15-20 minutes).<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span lang="EN-US" style="color:black">Looking forward to seeing you live or on Zoom:
</span><a href="https://chalmers.zoom.us/j/63018620593#success"><span lang="EN-US">https://chalmers.zoom.us/j/63018620593#success</span></a><span style="color:black">
</span><span lang="EN-US" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black">Best regards, <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black">Alexandra, Philippe, Christoph, and Janine<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
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