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<p class="MsoNormal"><a name="_Hlk152055189"><b><span lang="EN-US" style="font-size:24.0pt;line-height:105%;color:black">SmallTalk
</span></b></a><span style="mso-bookmark:_Hlk152055189"><b><span lang="EN-US" style="font-size:14.0pt;line-height:105%;color:black">[about Nanoscience]</span></b></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black"><o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><b><span lang="EN-US" style="color:black">On Monday </span></b></span><span style="mso-bookmark:_Hlk152055189"><b><span lang="EN-US">February 19th
</span></b></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">at 15.00h</span></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US">
<span style="color:black">we welcome you all to our SmallTalk seminar series. You are welcome to join us in lecture hall <b>Kollektorn, MC2 with fika</b> or on zoom.<o:p></o:p></span></span></span></p>
<h1><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="font-size:11.0pt;color:black;font-weight:normal">Our speaker is
</span></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="font-size:11.0pt;color:black">Luis Mario Leal Garza</span></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="font-size:11.0pt;color:black;font-weight:normal">,
Doctoral Student, Chemical Biology, Life Sciences. The seminar is titled β</span></span><span style="mso-bookmark:_Hlk152055189"><span class="text-normal"><span lang="EN-US" style="font-size:11.0pt;font-weight:normal">βDe novo assembly of yeast genomes using
optical genome mapping</span></span></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="font-size:11.0pt;color:black;font-weight:normal">β.</span></span><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="font-size:11.0pt;font-weight:normal"><o:p></o:p></span></span></h1>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">Abstract:<o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">Optical genome mapping (OGM) is a technique that can facilitate genome assemblies and detect structural variations in genomes, overcoming limitations of traditional
techniques. In this study, we use a nanofluidic device and competitive binding labeling to stretch and label DNA for its imaging. Computational methods are then used to de novo assemble the genomes of two model yeasts. Our results demonstrate the ability of
OGM to extend genome coverage in comparison to traditional genome assemblies.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">The seminar is divided into two parts, where the first part consists of a pure overview of the field and is held on a generally accessible level (10<span class="apple-converted-space"> </span>min).
The second part will be more technical (15-20 minutes).<o:p></o:p></span></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">Looking forward to seeing you live or on Zoom:
</span></span><a href="https://chalmers.zoom.us/j/61929604403#success"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US">https://chalmers.zoom.us/j/61929604403#success</span></span><span style="mso-bookmark:_Hlk152055189"></span></a><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black"><o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">Best regards, <o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk152055189"><span lang="EN-US" style="color:black">Angela, Nils, Christoph, and Janine</span></span><span lang="EN-US" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
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